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Colonoscopy Preparation in Children: Safety, Efficacy, and Tolerance of High- Versus Low-Volume Cleansing Methods

 

作者: da Silva,   Mary Briars,   Graham Patrick,   Mark Cleghorn,   Geoffrey Shepherd,  

 

期刊: Journal of Pediatric Gastroenterology and Nutrition  (OVID Available online 1997)
卷期: Volume 24, issue 1  

页码: 33-37

 

ISSN:0277-2116

 

年代: 1997

 

出版商: OVID

 

关键词: Colonoscopy preparation;Colonic lavage;Colonic cleansing

 

数据来源: OVID

 

摘要:

Background:The use of large-volume electrolyte balanced solutions as preparation for colonoscopy often results in poor patient compliance and acceptance. The tolerance, safety, and efficacy of high-versus low-volume colon-cleansing methods as preparation for colonoscopy in children were compared by randomized operator-blinded trial.Methods:Twenty-nine children ages 3.6-14.6 years had either high-volume nasogastric balanced polyethylene glycol electrolyte lavage (20 ml/kg/h) until the effluent was clear (n = 15), or two oral doses of sodium phosphate solution (22.5-45 ml) separated by oral fluid intake (n = 14).Results:Both preparations were equally effective. The low-volume preparation was better tolerated and caused less discomfort that the high-volume preparation, judging by serial nurse observations. The incidence of abdominal symptoms, diarrhea, sleep disturbance, and vomiting was not significantly different between the two groups. Both groups had a small reduction in mean hematocrit and serum calcium levels. The sodium phosphate preparation caused increases in mean serum sodium concentrations from 140 to 145 mmol/L and serum phosphate concentrations from 1.41 to 2.53 mmol/L. Ten hours after the commencement of the preanesthetic fast, these concentrations had returned to normal.Conclusions:There are advantages in terms of tolerance, discomfort, and case of administration with acceptable colonic cleansing with the use of the less-invasive oral sodium phosphate low-volume colon-cleansing preparation in children. Safe use requires ensuring an adequate oral fluid intake during the preparation time and avoidance of use in patients with renal insufficiency.

 



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