Colonoscopy Preparation in Children: Safety, Efficacy, and Tolerance of High- Versus Low-Volume Cleansing Methods
作者:
da Silva,
Mary Briars,
Graham Patrick,
Mark Cleghorn,
Geoffrey Shepherd,
期刊:
Journal of Pediatric Gastroenterology and Nutrition
(OVID Available online 1997)
卷期:
Volume 24,
issue 1
页码: 33-37
ISSN:0277-2116
年代: 1997
出版商: OVID
关键词: Colonoscopy preparation;Colonic lavage;Colonic cleansing
数据来源: OVID
摘要:
Background:The use of large-volume electrolyte balanced solutions as preparation for colonoscopy often results in poor patient compliance and acceptance. The tolerance, safety, and efficacy of high-versus low-volume colon-cleansing methods as preparation for colonoscopy in children were compared by randomized operator-blinded trial.Methods:Twenty-nine children ages 3.6-14.6 years had either high-volume nasogastric balanced polyethylene glycol electrolyte lavage (20 ml/kg/h) until the effluent was clear (n = 15), or two oral doses of sodium phosphate solution (22.5-45 ml) separated by oral fluid intake (n = 14).Results:Both preparations were equally effective. The low-volume preparation was better tolerated and caused less discomfort that the high-volume preparation, judging by serial nurse observations. The incidence of abdominal symptoms, diarrhea, sleep disturbance, and vomiting was not significantly different between the two groups. Both groups had a small reduction in mean hematocrit and serum calcium levels. The sodium phosphate preparation caused increases in mean serum sodium concentrations from 140 to 145 mmol/L and serum phosphate concentrations from 1.41 to 2.53 mmol/L. Ten hours after the commencement of the preanesthetic fast, these concentrations had returned to normal.Conclusions:There are advantages in terms of tolerance, discomfort, and case of administration with acceptable colonic cleansing with the use of the less-invasive oral sodium phosphate low-volume colon-cleansing preparation in children. Safe use requires ensuring an adequate oral fluid intake during the preparation time and avoidance of use in patients with renal insufficiency.
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