Hematoporphyrin photodynamic therapy: Is there truly a future in head and neck oncology? Reflections on a 5‐year experience
作者:
Jack L. Gluckman,
期刊:
The Laryngoscope
(WILEY Available online 1991)
卷期:
Volume 101,
issue 1
页码: 36-42
ISSN:0023-852X
年代: 1991
DOI:10.1288/00005537-199101000-00007
出版商: John Wiley&Sons, Inc.
数据来源: WILEY
摘要:
AbstractPhotodynamic therapy, which consists of the selective destruction of tumors using a combination of a photosensitizer administered systemically (dihe‐matoporphyrin ether) and an argon dye‐pumped laser, has provoked profound interest amongst oncologists and has particularly titillated head and neck oncologists with its potential. Unfortunately, no multi‐institutional trials for head and neck tumors have been introduced, and the literature is replete with anecdotal reports from individual researchers on the management of advanced cancers for palliation, superficial early cancers, and field cancerization of the mucosa (“condemned mucosa”)‐ A personal 5‐year experience with 41 head and neck cancers was reviewed, as was the current literature. An attempt was made to place in perspective the true role and future direction of th
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