A functional factor X deficiency
作者:
Paul Sun,
Jane Hata,
John Bauer,
Carolyn Haibach,
Doug Campbell,
Medhi Farhangi,
Dan Smith,
期刊:
American Journal of Hematology
(WILEY Available online 1995)
卷期:
Volume 48,
issue 1
页码: 1-4
ISSN:0361-8609
年代: 1995
DOI:10.1002/ajh.2830480102
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: factor X;coagulation factor deficiency
数据来源: WILEY
摘要:
AbstractA functional factor X deficiency is described which caused pronounced reduction in the in vitro activation of the extrinsic system while marginally affecting the in vitro activation of the intrinsic pathway. All studies were normal with the exception of a prolonged PT, an elevated factor X antigen, and low factor X activity. Western blot analysis revealed the presence of two factor X species. The abnormal molecule was of higher molecular weight. Interestingly, there was no bleeding associated with this deficiency. The biochemical basis of this defect is currently under investigation. ©1995 Wiley‐Liss, I
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