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Undertreatment of hypertension in community‐dwelling older adultsa drug‐utilization study in Dicomano, Italy

 

作者: Mauro Bari,   Francesca Salti,   Monica Nardi,   Marco Pahor,   Carmela Fusco,   Elisabetta Tonon,   Andrea Ungar,   Riccardo Pini,   Giulio Masotti,   Niccolò Marchionni,  

 

期刊: Journal of Hypertension  (OVID Available online 1999)
卷期: Volume 17, issue 11  

页码: 1633-1640

 

ISSN:0263-6352

 

年代: 1999

 

出版商: OVID

 

关键词: hypertension;elderly;drug therapy;undertreatment;ICARe Dicomano study

 

数据来源: OVID

 

摘要:

ObjectiveTo define: (1) the prevalence of and (2) factors associated with undertreatment of hypertension in older persons; and (3) the prevalence of specific drug regimens and reasons for their selection.ParticipantsCross-sectional survey of persons aged ≥ 65 years living in Dicomano, Italy.Main outcome measuresPrevalence of untreated and uncontrolled hypertension, both defined on the basis of two blood pressure (BP) cut-off points (≥ 140/90 and ≥ 160/90 mmHg) and of the presence of pharmacological treatment. Predictors of undertreatment were analysed for the higher BP cut-off only.ResultsFive hundred of 692 (72.3%) and 380/692 (54.9%) participants met the 140/90 and the 160/90 mmHg BP criterion, respectively. Of the latter, 162 (42.6%) were untreated, 119 (31.3%) had uncontrolled and 99 (26.1%) controlled hypertension. Women [odds ratio (OR), 0.4; 95% confidence interval (CI), 0.2–0.7], participants with coronary artery disease (CAD) (OR, 0.2; 95% CI, 0.1–0.6), stroke (OR, 0.3; 95% CI, 0.1–0.7), and preserved cognitive status (Mini Mental State Examination score >21: 0.3; 95% CI, 0.2–0.7) were more frequently treated. Uncontrolled hypertension was less likely in women (OR, 0.5; 95% CI, 0.3–1.0) and CAD patients (OR, 0.3; 95% CI, 0.1–0.7). Angiotensin converting enzyme (ACE)-inhibitors (55%), calcium (Ca)-antagonists (31%) and diuretics (20%) were the drugs most commonly prescribed. ACE-inhibitors were preferred, and diuretics rarely used, in diabetic subjects. Ca-antagonists were used mostly in CAD participants.ConclusionsHypertension is undertreated in the majority of noninstitutionalized older adults, especially in men with impaired cognition and no vascular disease. Drug regimens are mostly based on ACE-inhibitors and Ca-antagonists, as a result of associated clinical conditions, requiring individualized treatment.

 

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