The spatio-temporal variability of daily precipitation series was investigated in a semiarid region of central Macedonia in northern Greece, Ten years of daily rainfall records for seven stations in the region constituted the data base. The spatial characteristics were examined by drawing composite correlation diagrams for the cool (October-March) season and the warm (April-September) season, and the results confirmed the regional homogeneity of the data sets. Furthermore, the temporal analysis indicated that the non-rainy days constituted the major portion of days throughout the year at all the stations. Similarly, light rainfall represented the majority of rainy days. Moreover, the annual rainfall variation showed high values in March, April and November with low values occurring in the summer and autumn. A sharp increase of rainfall between the 185th and the 195th day of the year must be taken into account when the harvest is scheduled. Harmonic and Power Spectrum analyses applied to the annual variation of rain depths using 5-day intervals revealed significant periodicities of 26, 122, 365 and 55 days. Finally the analysis of the annual variation of rain occurrences. revealed periodicities of 365 and 122 days.