Failure of young goats to acquire resistance toHaemonchus contortus
作者:
W.E. Pomroy,
W.A.G. Charleston,
期刊:
New Zealand Veterinary Journal
(Taylor Available online 1989)
卷期:
Volume 37,
issue 1
页码: 23-26
ISSN:0048-0169
年代: 1989
DOI:10.1080/00480169.1989.35542
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Two experiments were carried out to investigate the acquisition by goats of resistance toHaemonchus contortus.In Experiment 1, five Saanen wethers reared worm-free and averaging 51/2 months of age at the start of the experiment, were dosed with 200H. contortusinfective larvae three times per week for 10 weeks (approximately 23 infective larvae/kg mean initial liveweight/week) and then given anthelmintic treatment. Each goat and an equal number of worm-free controls were then challenged with 10,000 infective larvae. Post mortem worm counts were carried out 30 days later. In Experiment 2, eight worm-free Saanen wethers, 14 months old at the start of the experiment, were dosed with 825 infective larvae per week for 14 weeks (approximately 23 infective larvae/kg mean initial liveweight/week) except for one week when only 300 larvae were given and one week when no larvae were given. After anthelmintic treatment, each received, together with seven worm-free control animals, a challenge dose of 15,000 infective larvae. Post-mortem worm counts were carried out 28 days later. There were no significant dii- ferences in post-mortem worm counts between previously infected and uninfected groups in either experiment. In both experiments, serum pepsinogen values rose significantly as a result of infection but there was no significant (p>0.5) correlation between worm counts and pepsinogen values on the day of slaughter.
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