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Deletion 9p22‐pter and loss of Y as primary chromosome abnormalities in a squamous cell carcinoma of the vocal cord

 

作者: Maria J. Worsham,   Michael J. Benninger,   Richard J. Zarbo,   Thomas E. Carey,   Daniel L. Van Dyke,  

 

期刊: Genes, Chromosomes and Cancer  （WILEY Available online 1993）
卷期: Volume 6, issue 1  

页码: 58-60

 

ISSN:1045-2257

 

年代: 1993

 

DOI:10.1002/gcc.2870060111

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractLoss of distal 9p is a common genetic alteration in squamous cell carcinoma of the head and neck. A vocal cord lesion incorporating a carcinoma‐in‐situ and a focus of invasive carcinoma revealed loss of the Y chromosome and a 9p22 rearrangement with loss of 9p22‐pter. Loss of 9p22‐pter appears to be a primary autosomal abnormality in this squamous cell carcinoma. © 1993 Wiley

 

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