Arteriovenous carbon dioxide and pH gradients during cardiac arrest
作者:
WILLIAM,
GRUNDLER MAX,
WEIL ERIC,
期刊:
Circulation
(OVID Available online 1986)
卷期:
Volume 74,
issue 5
页码: 1071-1074
ISSN:0009-7322
年代: 1986
出版商: OVID
数据来源: OVID
摘要:
In a porcine preparation of cardiac arrest, we demonstrated that there is a marked paradox of venous acidemia and arterial alkalemia. This paradox is related to decreased clearance of CO2 from the lungs when pulmonary blood flow is critically reduced. Accordingly, increased venous Pco2 rather than metabolic acidosis due to lactic acidosis predominates during the initial 8 min of cardiopulmonary resuscitation. Arterial blood gases fail as indicators of systemic acid-base status and therefore as indicators of tissue acidosis.
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