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Human Monoclonal Antibodies: Achievement and Potential

 

作者: BurtonDennis R.,  

 

期刊: Hospital Practice  （Taylor Available online 1992）
卷期: Volume 27, issue 8  

页码: 67-74

 

ISSN:2154-8331

 

年代: 1992

 

DOI:10.1080/21548331.1992.11705469

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

The concept of monoclonal antibodies evoked great excitement when first described, but usefulness has been limited by their murine origin and consequent immunogenicity. Human monoclonal antibodies—which would obviate xenotypic responses—can now be produced. Clinical implications—including use against HIV—are discussed.

 

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