A case of endobronchial Kaposi's sarcoma is described in a 50-year-old man seropositive for human immunodeficiency virus. He had a history ofPneumocystis cariniipneumonia and cryptococcal meningitis. He presented without any pulmonary symptoms. Computed tomography of the chest showed bilateral nodules. Bronchoscopy demonstrated well-demarcated dark-brown discrete lesions that were not raised. Video-assisted thoracoscopic biopsy of the lung nodule demonstrated pathologic findings consistent with Kaposi's sarcoma. The patient was treated with highly active antiretroviral therapy and had regression of the disease. This case emphasizes the importance of bronchoscopy in the diagnosis and the effectiveness of highly active antiretroviral therapy in the treatment of pulmonary Kaposi's sarcoma.