ANIMAL MODELS FOR TESTING TOPICAL CORTICOSTEROID POTENCY: A REVIEW AND SOME SUGGESTED NEW APPROACHES
作者:
NEAL S. PENNEYS,
期刊:
International Journal of Dermatology
(WILEY Available online 1992)
卷期:
Volume 31,
issue 1
页码: 6-8
ISSN:0011-9059
年代: 1992
DOI:10.1111/j.1365-4362.1992.tb04005.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractAnimal models allow for testing the potency of topical corticosteroids by measuring their effects on induced conditions that are analogous to human skin disease. Animal models can examine the anti‐inflammatory, anti‐allergic, antiproliferative, and atrophogenic effects of topical corticosteroids. These test models as they are currently applied are relatively imprecise; however, innovations using newly available histologic, autoradiographic, and biochemical techniques have great potential for precisely quantitating the effects of corticosteroids in animal model syst
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