Phytoremediation is a relatively new technology, whose practical application still requires more studies in various fields, including biology, sociology, legislation, and education. In order to establish a phytoremediation site, it is necessary that: (1) no detrimental effects are transferred to the surrounding environment, (2) the management of the site is effective from an economical and social point of view, and (3) the overall strategy is economically advantageous over other techniques. Waste management and treatment have a great social and psychological impact. Therefore, the public acceptance of phytoremediation application also depends on appropriate measures taken to inform people about the advantages and safety of this technology. Another very important aspect is the regulatory acceptance of phytoremediation as a valid alternative to other remediation or decontamination strategies. In this case the safety of the procedure utilized and the absence of environmental impacts is mandatory. In order to integrate these different aspects with modern strategies for phytoremediation, it is important that scientists, economists, lawyers, and managers from public and private agencies and institutions are able to share their own needs, experiences, and results. PHYTONET is a thematic network created with the purpose of addressing all of these issues and links with other networks operating on similar or complementary subjects.