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Alpha1‐Acid Glycoprotein, Age, and Sex in Mood Disorders

 

作者: Robert Young,   Ashok Patel,   Barnett Meyers,   Tatsuyuki Kakuma,   George Alexopoulos,  

 

期刊: American Journal of Geriatric Psychiatry  （OVID Available online 1999）
卷期: Volume 7, issue 4  

页码: 331-334

 

ISSN:1064-7481

 

年代: 1999

 

出版商: OVID

 

关键词: Mood Disorders;Neurophysiology;Antidepressants;Neuroleptics

 

数据来源: OVID

 

摘要:

Serum alpha1-acid glycoprotein (AAG) reportedly can increase with age in the normal population, especially among women. In 33 patients with unipolar major depression or bipolar disorder, serum AAG was measured by age. The authors noted a positive association with age, particularly in depressed female patients (n=18; rs=0.61; P<0.01). The authors discuss implications for drug pharmacokinetics. Investigation of AAG in mood disorders needs to take age and sex into consideration.

 

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