Deswelling of the Cornea After Hypoxia
作者:
MURRAY JOHNSON,
ROGER BOLTZ,
LOUIS GODIO,
期刊:
American Journal of Optometry and Physiological Optics
(OVID Available online 1985)
卷期:
Volume 62,
issue 11
页码: 768-773
ISSN:0093-7002
年代: 1985
出版商: OVID
关键词: contact lens;corneal thickness;corneal deswelling;corneal oxygen consumption;corneal recovery
数据来源: OVID
摘要:
Central corneal thickness changes were monitored in nine subjects who wore low water content hydrogel lenses of varying thickness for 3 h in the open and closed eye conditions. At the end of 3 h of lens wear, corneal de-swelling to prelens thickness for the different levels of hypoxia was determined by pachometry performed every 5 min for the first 30 min, every 10 min for the next 40 min, and every 15 min thereafter. Examination of the individual deswelling profiles indicates (1) a biphasic response in those with corneal edema greater than 14%, and (2) a large portion of the deswelling occurred during the first 30 min, followed by a more gradual rate until baseline was reached. Small amounts of corneal edema (less than 5%) required up to 25 min to return to baseline, whereas 6 to 15% required 30 to 70 min, and 20% required 95 min. The time taken for the cornea to deswell to baseline was linearly related to the amount of corneal swelling (r = 0.88; p < 0.0001).
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