Correlative transmission and scanning electron microscopy of the initial mineralization of healing alveolar bone in rats
作者:
J. Sela,
I.A. Bab,
期刊:
Cells Tissues Organs
(Karger Available online 1979)
卷期:
Volume 105,
issue 4
页码: 401-408
ISSN:1422-6405
年代: 1979
DOI:10.1159/000145146
出版商: S. Karger AG
关键词: Matrix vesicles;Mineralization;Bone socket healing;TEM;SEM;Calcospherites
数据来源: Karger
摘要:
Primary mineralization in healing sockets after extraction of molar teeth was studied in rats. The observations obtained by scanning electron microscopy were correlated by transmission electron microscopy. The process is characterized by abundance of extracellular matrix vesicles distributed between the forming cells and the calcifying fronts. The occurrence of osmiophilic material and solitary hydroxyapatite crystals within the vesicles was followed by accumulation of hydroxyapatite crystals, disappearance of the vesicular membrane and formation of calcospherites that conglomerate into calcified fronts. The process described here in bone healing is essentially similar to primary mineralization in other normal and pathological calcified tissues.
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