Cortical Histopathology following Stimulation with Metallic and Carbon Electrodes; pp. 126–141
作者:
J.J. Bernstein,
P.F. Johnson,
L.L. Hench,
G. Hunter,
W.W. Dawson,
期刊:
Brain, Behavior and Evolution
(Karger Available online 1977)
卷期:
Volume 14,
issue 1-2
页码: 126-141
ISSN:0006-8977
年代: 1977
DOI:10.1159/000125579
出版商: S. Karger AG
关键词: Electrode-tissue interaction;Stimulation and brain pathology;Neural prostheses
数据来源: Karger
摘要:
Stimulation of the cat striate cortex with polished 1 mm2 gold, platinum, rhodium or carbon electrodes for 40 h, at 50 Hz, and 0.5 msec duration, results in tissue damage at current densities of 0.6 A/cm2. At 0.1 A/cm2 rhodium and carbon were toxic to brain. In vitro gold and platinum corroded after 1,500–2,300 h of testing in simulated cerebrospinal fluid. The materials utilized are not suitable for long-term chronic electrodes for neural prosthetic
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