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Cortical Histopathology following Stimulation with Metallic and Carbon Electrodes; pp. 126–141

 

作者: J.J. Bernstein,   P.F. Johnson,   L.L. Hench,   G. Hunter,   W.W. Dawson,  

 

期刊: Brain, Behavior and Evolution  (Karger Available online 1977)
卷期: Volume 14, issue 1-2  

页码: 126-141

 

ISSN:0006-8977

 

年代: 1977

 

DOI:10.1159/000125579

 

出版商: S. Karger AG

 

关键词: Electrode-tissue interaction;Stimulation and brain pathology;Neural prostheses

 

数据来源: Karger

 

摘要:

Stimulation of the cat striate cortex with polished 1 mm2 gold, platinum, rhodium or carbon electrodes for 40 h, at 50 Hz, and 0.5 msec duration, results in tissue damage at current densities of 0.6 A/cm2. At 0.1 A/cm2 rhodium and carbon were toxic to brain. In vitro gold and platinum corroded after 1,500–2,300 h of testing in simulated cerebrospinal fluid. The materials utilized are not suitable for long-term chronic electrodes for neural prosthetic

 

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