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Structure and Function of Interleukins 4 and 5

 

作者: Tasuku Honjo,   Yoshio Yaoita,   Tatsuo Kinashi,   Yoshihiko Noma,   Takayuki Naito,   Chihiro Azuma,   Eva Severinson,   Paschalis Sideras,   Susanna Bergstedt‐Lindqvist,   Kiyoshi Takatsu,   Akira Tominaga,   Nobuhiko Harada,   Toshizumi Tanabe,   Mikio Konishi,   Masazumi Takahashi,   Fumihiko Matsuda,  

 

期刊: Pediatrics International  （WILEY Available online 1987）
卷期: Volume 29, issue 4  

页码: 546-551

 

ISSN:1328-8067

 

年代: 1987

 

DOI:10.1111/j.1442-200X.1987.tb02237.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

AbstractWe have cloned cDNAs for IgG, induction factor and T cell replacing factor. The recombinant factors were shown to have multiple activities on B cells, which could explain most, if not all, of B cell growth and differentiation factor activities so far claimed. Since the recombinant factors were also shown to affect bone marrow‐derived cells other than B cells, the names of interleukins 4 and 5 were proposed for IgG1induction factor and T cell replacing factor, respectivel

 

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