SummaryA case of angio-immunoblastic lymphadeno pathy is reported. The patient is a 56-year old female. Shexhibited a generalized lymphadenopathy of acute onset, hepatosplenomegaly, edema, rash and general symptoms. Polyclonal IgVI dysproteinaemia was present. Deterioration of the patient’s condition was accompanied by a rarely described aregenerative anaemia. Pathological findings before and during steroid treatment are described in detail. Treatment seems to have caused hyalinisation of the vessels and differentiation of the cell population to small lymphocytes with disappearance of younger immunoblasts and plasmocytes.