Cocaine abuse is a public health problem of epidemic proportions. Prominent victims have succumbed to its use, including athletes, movie stars, and businessmen. Whether through ignorance or misinformation, many who have neglected to understand the health hazards of cocaine have paid with their life. This article presents a concise review of the complications of cocaine use as seen in both my practice and in the corresponding literature search, with emphasis on its impact on the nervous system, since stroke and panic attacks seem to be the most frequent medical complications. This article further offers a succinct approach to the diagnosis and treatment of cocaine abuse.