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Efficacy of Trazodone as an Anti-Obsessional Agent

 

作者: Ashoka Prasad,  

 

期刊: Neuropsychobiology  （Karger Available online 1986）
卷期: Volume 15, issue 1  

页码: 19-21

 

ISSN:0302-282X

 

年代: 1986

 

DOI:10.1159/000118274

 

出版商: S. Karger AG

 

关键词: Obsessive-compulsive neurosis;Serotonin;Trazodone;Leyton obsessional inventory;Montgomery-Asberg scale

 

数据来源: Karger

 

摘要:

Eight patients with chronic obsessive-compulsive neurosis were subjected to trazodone, an antidepressant acting on the serotonergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement had a significantly higher trait score than the others on psychometric ratings.

 

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