Effect of Thiamin Status on the Metabolism of Linamarin in Rats
作者:
I.B. Umoh,
F.O. Ogunkoya,
E.N. Maduagwu,
O.L. Oke,
期刊:
Annals of Nutrition and Metabolism
(Karger Available online 1985)
卷期:
Volume 29,
issue 5
页码: 319-324
ISSN:0250-6807
年代: 1985
DOI:10.1159/000176987
出版商: S. Karger AG
关键词: Thiamin;Metabolism;Linamarin
数据来源: Karger
摘要:
The effect of graded levels of thiamin on the metabolism of linamarin was investigated in rats. It was observed that on a diet deficient in thiamin, a large amount of linamarin was recovered unchanged in the urine, together with significantly more thiocyanate (SCN–) relative to the control. The least amount of thiocyanate (p < 0.05 relative to control) was found in animals receiving the highest amount (twice daily requirement) of thiamin in the diet; but the amount of unmetabolized linamarin was similar to the control. It is suggested that thiamin deficiency may be implicated in the aetiology of tropical ataxic neuropathy (TAN) through the thiocyanate overload in people eating large amounts of cassava and cassava derivatives which contain linamari
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