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An Analysis of Contaminated Well Water and Health Effects in Woburn, Massachusetts

 

作者: S.W. Lagakos,   B.J. Wessen,   M. Zelen,  

 

期刊: Journal of the American Statistical Association  (Taylor Available online 1986)
卷期: Volume 81, issue 395  

页码: 583-596

 

ISSN:0162-1459

 

年代: 1986

 

DOI:10.1080/01621459.1986.10478307

 

出版商: Taylor & Francis Group

 

关键词: Environmental exposure;Health survey;Observational study;Proportional hazards model;Time-dependent covariate

 

数据来源: Taylor

 

摘要:

In 1979, two of the eight municipal wells servicing Woburn, Massachusetts, were discovered to be contaminated with several chlorinated organics. Shortly afterwards, the town was found to have an elevated rate of childhood leukemia. Using recent information about the space—time distribution of water from the two contaminated wells, we find positive statistical associations between access to this water and the incidence rates of childhood leukemia, perinatal deaths (1970–1982), two of five categories of congenital anomalies, and two of nine categories of childhood disorders. We find no associations with spontaneous abortions, low birth weight, or the other categories of congenital anomalies and childhood disorders. This article discussed these results and other features of the data relevant to their interpretation.

 

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