PRODUCTION OF A CORTICOTROPHIN‐LIKE INTERMEDIATE LOBE PEPTIDE AND OF CORTICOTROPHIN BY A BRONCHIAL CARCINOID TUMOUR
作者:
J. G. RATCLIFFE,
A. P. SCOTT,
H. P. J. BENNETT,
P. J. LOWRY,
C. McMARTIN,
J. A. STRONG,
P. R. WALBAUM,
期刊:
Clinical Endocrinology
(WILEY Available online 1973)
卷期:
Volume 2,
issue 1
页码: 51-55
ISSN:0300-0664
年代: 1973
DOI:10.1111/j.1365-2265.1973.tb03484.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYThe isolation and partial characterization of a peptide with C‐terminal corticotrophic immunoactivity from a bronchial carcinoid tumour associated with the ectopic ACTH syndrome is described. It resembles corticotrophin‐like intermediate lobe peptide (CLIP) in amino acid composition and end group analyses. It is suggested that the specific measurement of circulating CLIP may serve as a biochemical marker of tumour activ
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