Rapid increase of both HIV‐1 infection and syphilis among pregnant women in Nairobi, Kenya
作者:
Marleen Temmerman,
Fatma Ali,
Jackoniah Ndinya-Achola,
Stephen Moses,
Francis Plummer,
Peter Piot,
期刊:
AIDS
(OVID Available online 1992)
卷期:
Volume 6,
issue 10
页码: 1181-1186
ISSN:0269-9370
年代: 1992
出版商: OVID
关键词: HIV-1;syphilis;antenatal;Kenya;sexually transmitted disease
数据来源: OVID
摘要:
ObjectiveTo determine the prevalence of HIV-1 and syphilis antibodies in a population of pregnant women in Nairobi, Kenya, between 1989 and 1991.MethodsAs part of an ongoing prospective study on the effect of HIV-1 infection and sexually transmitted diseases, 4883 pregnant women were screened for HIV-1 and syphilis antibodies in one health-centre in Nairobi.ResultsHIV-1 seroprevalence increased from 6.5 to 13.0% (PP= 0.002), while there was no change in gonococcal infection rates. The most rapid increase in HIV-1 prevalence was observed in women aged less than 25 years. There was no evidence of demographic fluctuations in the population during this time, or of changes in sexual behaviour, except that fewer women enrolled in 1991 reported having more than one sex partner, compared with women enrolled in 1989 (39.1 versus 20.0%;P= 0.0001). HIV-1-seropositive women were more likely to be seroreactive for syphilis than HIV-1-seronegative mothers (7.7 versus 3.2%; odds ratio = 2.5; 95% confidence interval, 1.7–3.8;PConclusionThese data confirm an association between HIV-1 and syphilis infection, and indicate that both are spreading rapidly among women in Nairobi outside high-risk groups. Increased efforts to control both infections are urgently required.
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