Creutzfeldt‐Jakob Disease Transmitted by a Cadaveric Dura Mater Graft
作者:
Shozo Yamada,
Tadashi Aiba,
Yuzo Endo,
Mitsuru Hara,
Tetsuyuki Kitamoto,
Jun Tateishi,
期刊:
Neurosurgery
(OVID Available online 1994)
卷期:
Volume 34,
issue 4
页码: 740-744
ISSN:0148-396X
年代: 1994
出版商: OVID
关键词: Cadaveric dura;Creutzfeldt-Jakob disease;Gene analysis;Immunohistochemistry;Prion protein;Western blot analysis
数据来源: OVID
摘要:
WE REPORT A case of Creutzfeldt-Jakob disease developing in a 31-year-old woman 56 months after she received a cadaveric dura mater graft after the removal of a giant pituitary adenoma. Creutzfeldt-Jakob disease was confirmed by a brain autopsy and the existence of an abnormal isoform of prion protein, verified by both immunohistochemical and Western blot analysis. Moreover, prion protein gene analysis was shown in this case to possess a wild-type genotype. The characteristics of Creutzfeldt-Jakob disease after a cadaveric dura mater graft are reviewed and discussed.
返 回