Oligoribonucleotide synthesis. IX. Synthesis of sequences corresponding to the dihydrouridine loop neck region common in several transfer RNA molecules
作者:
T. E. England,
Thomas Neilson,
期刊:
Canadian Journal of Chemistry
(NRC Available online 1976)
卷期:
Volume 54,
issue 11
页码: 1714-1721
ISSN:0008-4042
年代: 1976
DOI:10.1139/v76-244
出版商: NRC Research Press
数据来源: NRC
摘要:
The syntheses of the oligoribonucleotides GpApGpC, GpCpUpC, and ApGpCpUpC by an improved phosphotriester method are described. These sequences are found in the double-stranded region adjacent to the dihydrouridine loop of several transfer RNAs. Of special significance is the improvement in yields that the activating agent, mesitylenesulfonyl triazolide, provides in coupling reactions involving purine residues.
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