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Effects of Cisapride on the Esophageal Motor Function of Patients with Progressive Systemic Sclerosis or Mixed Connective Tissue Disease

 

作者: A.J. Limburg,   A.J. Smit,   J.H. Kleibeuker,  

 

期刊: Digestion  （Karger Available online 1991）
卷期: Volume 49, issue 3  

页码: 156-160

 

ISSN:0012-2823

 

年代: 1991

 

DOI:10.1159/000200715

 

出版商: S. Karger AG

 

关键词: Cisapride;Esophageal motility;Lower esophageal sphincter;Progressive systemic sclerosis;Mixed connective tissue disease

 

数据来源: Karger

 

摘要:

In a double-blind crossover study lower esophageal sphincter pressure and distal esophageal motility were studied in 10 patients with progressive systemic sclerosis or mixed connective tissue disease, following a single intravenous dose of cisapride or placebo. The measurements were carried out under basal conditions and 30 min after intravenous administration of 10 mg cisapride or placebo. No effects on lower esophageal sphincter pressure or distal esophageal motility were observed.

 

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