Immunohistochemical localization of glutathione peroxidase in ocular tissue
作者:
AtallaLily R.,
SevanianAlex,
RaoNarsing A.,
期刊:
Current Eye Research
(Taylor Available online 1988)
卷期:
Volume 7,
issue 10
页码: 1023-1027
ISSN:0271-3683
年代: 1988
DOI:10.3109/02713688809015149
出版商: Taylor&Francis
数据来源: Taylor
摘要:
In this study enzyme glutathione peroxidase was localized in ocular tissue of Lewis rats using the peroxidase antiperoxidase immunohistochemical technique. Antisera to glutathione peroxidase was raised in a rabbit. Immunoreactive glutathione peroxidase was found to be distributed predominantly in the corneal epithelium and endothelium, choroid, inner segment of photoreceptors and retinal pigmented epithelium. Its presence in these sites suggests an adaptation to oxidative stress where this antioxidant enzyme along with other antioxidant systems serves to prevent damage.
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