The effect of inorganic lead and/or a polychlorinated biphenyl on the developing immune system of mice
作者:
PatriciaA. Talcott,
LorenD. Koller,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1983)
卷期:
Volume 12,
issue 2-3
页码: 337-352
ISSN:0098-4108
年代: 1983
DOI:10.1080/15287398309530431
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Approximately 200 female Swiss‐Webster mice, six to eight weeks of age, were divided into eight groups. Three of these groups were fed 10, 100, or 250 ppm Aroclor 1254. One group was treated with 1000 ppm lead. Three groups were exposed simultaneously to lead and Aroclor 1254 at concentrations of 10 ppm PCB + 1000 ppm Pb, 100 ppm PCB + 7000 ppm Pb, and 250 ppm PCB + 7000 ppm Pb. Control mice received deionized water and rat food only. All groups were exposed for a period of 12 wk, then bred, with exposure continued throughout gestation and lactation. Offspring were weaned onto the control diet at 3 wk of age.
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