Copper uptake and resistance in bacteria
作者:
Donald A. Cooksey,
期刊:
Molecular Microbiology
(WILEY Available online 1993)
卷期:
Volume 7,
issue 1
页码: 1-5
ISSN:0950-382X
年代: 1993
DOI:10.1111/j.1365-2958.1993.tb01091.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryCopper ions are essential for bacteria but can cause a number of toxic cellular effects if levels of free ions are not controlled. Investigations of copper‐resistant bacteria have revealed several mechanisms, mostly plasmid‐determined, that prevent cellular uptake of high levels of free copper ions. However, these studies have also revealed that bacteria apparently have efficient chromosomally encoded systems for uptake and management of trace levels of copper. This review will explore the relationship of copper uptake systems to resistance mechanisms and the possibility that copper resistance has evolved directly through modification of chromosomal copper uptake ge
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