Lack of Hematologic Effects of Recent Ethanol Ingestion by Trauma Patients
作者:
Brian,
Erstad Cosimo,
Costa John,
Daller John,
期刊:
American Journal of Therapeutics
(OVID Available online 1999)
卷期:
Volume 6,
issue 6
页码: 293-302
ISSN:1075-2765
年代: 1999
出版商: OVID
关键词: ethanol;trauma;transfusion;coagulation;hematologic.
数据来源: OVID
摘要:
A retrospective investigation was conducted to determine if acute ethanol (EtOH) ingestion before injury leads to hematologic impairment as noted by coagulation and transfusion parameters. Patients older than 18 years of age were grouped according to the presence or absence of detectable EtOH concentrations in the blood, with further subdivision based on an Injury Severity Score of 8 or less or 9 or more. The following direct and indirect indicators of hematologic function were studied: volume of resuscitation fluids administered (including blood products), prothrombin time, partial thromboplastin time, and hematocrit. Of the 304 patients who were evaluated, 152 had detectable EtOH concentrations and 136 had andetectable EtOH concentrations; 16 patients had not been tested for blood EtOH concentrations and were excluded from the analysis. There were no significant differences between groups with regard to blood or fluid requirements or coagulation parameters. Detectable blood EtOH concentrations in trauma patients are not associated with significant changes in transfusion requirements or coagulation parameters compared to patients without detectable EtOH concentrations.
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