The Inverted Y-Chromosome Polymorphism in the Gujarati Muslim Indian Population of South Africa Has a Single Origin
作者:
Amanda Spurdle,
Trefor Jenkins,
期刊:
Human Heredity
(Karger Available online 1992)
卷期:
Volume 42,
issue 5
页码: 330-332
ISSN:0001-5652
年代: 1992
DOI:10.1159/000154093
出版商: S. Karger AG
关键词: Inv(Y) chromosome;Gujarati Muslims;49a RFLPs
数据来源: Karger
摘要:
Y-specific polymorphisms were studied in Gujarati Muslim Indians possessing a Y-chromosome pericentric inversion [inv(Y)] in an attempt to prove a common genetic origin for the inversion. The p49a/TaqI and p49a/PvuII haplotypes were determined for 9 normal and 8 inv(Y) Gujarati Muslim men. Men with the inversion possessed identical TaqI and PvuII profiles, as opposed to 7 different TaqI and 8 different PvuII haplotypes observed in the 9 normal men. These results provide conclusive evidence for a common genetic origin of the inverted Y chromosome observed in this Gujarati Muslim community.
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