Calcium Metabolism in Schizophrenic Patients on Long-Term Neuroleptic Therapy
作者:
P.C. Baastrup,
C. Christiansen,
I. Transbøl,
期刊:
Neuropsychobiology
(Karger Available online 1980)
卷期:
Volume 6,
issue 1
页码: 56-59
ISSN:0302-282X
年代: 1980
DOI:10.1159/000117734
出版商: S. Karger AG
关键词: Mineral metabolism;Osteopenia;Neuroleptic drugs;Schizophrenia
数据来源: Karger
摘要:
The bone mineral content (BMC) in both forearms (highly related to total body calcium) was measured in a large group of schizophrenic patients receiving neuroleptic drugs. The mean BMC value was 86% of normal (p < 0.001), and the decrease was independent of type of neuroleptic treatment. In contrast, the biochemical variables (serum calcium, magnesium, phosphate, and alkaline phosphatases) were virtually normal. This combination of osteopenia and normal biochemical variables suggests that schizophrenics have osteoporosis, be it due to the disease or the treatment gjven.
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