The acetylation‐deacetylation equilibrium of sulfadimidine in ruminant calves
作者:
J.F.M. Nouws,
T.B. Vree,
M. Tijhuis,
M. Baakman,
期刊:
Veterinary Quarterly
(Taylor Available online 1983)
卷期:
Volume 5,
issue 1
页码: 41-48
ISSN:0165-2176
年代: 1983
DOI:10.1080/01652176.1983.9693871
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Plasma disappearance curves of sulfadimidine (SDM) in calves show at high doses a pattern resembling that of capacity‐limited elimination. The half‐life of the first part of the elimination phase of SDM when administered at high doses ranged between 6.4 and 11.5 h, while that of the terminal end of the plasma concentration‐time curves was similar to that obtained at a low level application, ranging between 2.5 and 6.0 h.
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