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Surface Labelling of Senescent Chick Fibroblasts by Lactoperoxidase-Catalysed Iodination

 

作者: Y. Courtois,   R.C. Hughes,  

 

期刊: Gerontology  （Karger Available online 1976）
卷期: Volume 22, issue 5  

页码: 371-379

 

ISSN:0304-324X

 

年代: 1976

 

DOI:10.1159/000212149

 

出版商: S. Karger AG

 

关键词: Cell surface;Chick fibroblasts;lodine-125;Lactoperoxidase;Glycoprotein

 

数据来源: Karger

 

摘要:

Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec.wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend our previous observations on cell surface modifications in in vitro senescing fibroblasts.

 

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