Urinary Procoagulant Excretion and its Relation to Kidney Function
作者:
T. Matsumura,
M.P. Hutt,
K.N. von Kaulla,
期刊:
Nephron
(Karger Available online 1970)
卷期:
Volume 7,
issue 2
页码: 165-177
ISSN:1660-8151
年代: 1970
DOI:10.1159/000179818
出版商: S. Karger AG
数据来源: Karger
摘要:
A powerful procoagulant is normally excreted in large amounts in the urine of man, rats and rabbits. The secretion is not altered in a variety of diseases including hemorrhagic diathesis and thromboembolism. In parenchymatous kidney diseases, however, there is a marked reduction of procoagulant excretion. The procoagulant excretion is negatively correlated with BUN, blood creatinine and degree of proteinuria. With marked proteinuria in human or experimental renal disease, the procoagulant content per ml urine and the 24 h excretion drop to very low or zero values. In man, complete recovery of procoagulant excretion is obtained after homotransplantation of a well functioning kidney.
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