Acute Aluminum Toxicity Associated with Oral Citrate and Aluminum‐Containing Antacids
作者:
BY,
B. KIRSCHBAUM ANTON,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1989)
卷期:
Volume 297,
issue 1
页码: 9-11
ISSN:0002-9629
年代: 1989
出版商: OVID
关键词: Hyperaluminemia;Toxic Encephalopathy;Renal Failure
数据来源: OVID
摘要:
The authors report the development of a rapidly progressive encephalopathy marked by confusion, myoclonus, seizures, coma, and death in a group of women with renal failure who received an oral solution of citrate and aluminum hydroxide gel concurrently. Two patients were documented as having marked hyperaluminemia far exceeding blood aluminum levels encountered in the chronic state of aluminum intoxication. We ascribe the toxicity to enhanced gastrointestinal absorption of aluminum when complexed with citrate.
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