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Oral bioavailability of sulphamethoxydiazine, sulphathiazole and sulphamoxole in dwarf goats

 

作者: K. Weijkamp,   S.M. Faghihi,   S.M. Nijmeijer,   R. F. Witkamp,   A.S.P.J.A.M. van Miert,  

 

期刊: Veterinary Quarterly  （Taylor Available online 1994）
卷期: Volume 16, issue 1  

页码: 33-37

 

ISSN:0165-2176

 

年代: 1994

 

DOI:10.1080/01652176.1994.9694413

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

To get a better insight into the oral bioavailability of sulphonamides in ruminants, sulphamethoxydiazine (pKa 7.0), sulphathiazole (pKa 7.2), and sulphamoxole (pKa 7.4) were administered to dwarf goats (n=5). The drugs were given at 2‐week intervals by the intravenous or intraruminal route at a dose of 100 mg per kg body weight.

 

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