Abstract(Z)‐1,1‐Dichloro‐2‐(4‐benzyloxyphenyl)‐2,3‐bis(4‐methoxyphenyl)cyclopropane (5), a potential antitumor agent designed to treat breast cancer, was prepared in three steps. A stereospecific palladium‐catalyzed cross coupling reaction which provided the intermediate (Z)‐triaryl alkene4was a crucial step in the synthesis. Makosza phase transfer reaction on4gave the enantiomeric (Z)‐dichlorocyclopropane derivatives5which were resolved by semipreparative HPLC on a chiral stationary phase consisting of amylose tris‐3,5‐dimethylphenyl carbamate coated on silica ge