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Inhibition of Macrophage Superoxide Production by Two Prenylated Flavanones fromErythrina sigmoidea Hua

 

作者: N. Cotelle,   J-L Bernier,   J-P Catteau,   J-P Henichart,   D. Pesando,  

 

期刊: Natural Product Letters  （Taylor Available online 1993）
卷期: Volume 3, issue 1  

页码: 79-86

 

ISSN:1057-5634

 

年代: 1993

 

DOI:10.1080/10575639308043841

 

出版商: Taylor & Francis Group

 

关键词: Prenylated flavanones;antioxidant;O2−scavengers;NADPH oxidase;stable radicals

 

数据来源: Taylor

 

摘要:

Two prenylated flavanones namely sigmoidin A (SA) and sigmoidin B (SB) have been extracted fromErythrina sigmoidea Hua, a plant of Cameroon traditionally used in local medicine. An antioxidant activity was found and ascribed either to a direct reaction with O2−or to a direct and/or indirect action on the membrane-bound enzyme NADPH oxidase. The formation of stable radicals was also demonstrated by electron spin resonance spectroscopy (ESR) and related to the antioxidant activity.

 

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