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Familial Thrombosis Due to Antithrombin III Deficiency in a Greek Family

 

作者: N.E. Stathakis,   A.G. Papayannis,   M. Antonopoulos,   C. Gardikas,  

 

期刊: Acta Haematologica  （Karger Available online 1977）
卷期: Volume 57, issue 1  

页码: 47-54

 

ISSN:0001-5792

 

年代: 1977

 

DOI:10.1159/000207859

 

出版商: S. Karger AG

 

关键词: Antithrombin III deficiency;Coagulation;Familial thrombosis;Heparin cofactor;Thrombosis

 

数据来源: Karger

 

摘要:

A Greek family with hereditary antithrombin III (AT III) deficiency associated with venous thrombosis is reported. 5 members of the family were affected. In these patients, AT III and heparin cofactor activities were decreased. Immunoreactive AT III showed a positive correlation to both AT III and heparin cofactor activities. α2-Macroglobulin and α1-antitrypsin were normal. The pattern of inheritance of the defect is autosomal dominan

 

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