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Biosynthetic Capacities of Actinomycetes. 1 Screening for Secondary Metabolites by HPLC and UV-Visible Absorbance Spectral Libraries

 

作者: Hans-Peter Fiedler,  

 

期刊: Natural Product Letters  （Taylor Available online 1993）
卷期: Volume 2, issue 2  

页码: 119-128

 

ISSN:1057-5634

 

年代: 1993

 

DOI:10.1080/10575639308043796

 

出版商: Taylor & Francis Group

 

关键词: HPLC-UV-Vis data base;screening;actinomycetes

 

数据来源: Taylor

 

摘要:

Culture filtrates, their extracts and mycelium extracts of actinomycetes strains are analyzed by HPLC and diode-array detection. Comparing retention times and UV-visible spectra with data from known antibiotics and other metabolites stored in natural substance class libraries in a data base permit an effective screening for new secondary metabolites.

 

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