Prognostic Factors in Large-Cell Lymphomas
作者:
CoiffierBertrand,
LepageEric,
期刊:
Leukemia&Lymphoma
(Taylor Available online 1993)
卷期:
Volume 10,
issue sup1
页码: 57-60
ISSN:1042-8194
年代: 1993
DOI:10.3109/10428199309149113
出版商: Taylor&Francis
关键词: Prognostic factors;large cell lymphomas
数据来源: Taylor
摘要:
A review of the most significant prognostic factors found in large cell lymphomas is presented. Prognostic factors are divided in four categories: (a) those related to the patient: age at diagnosis; (b) those related to the tumor: stage, tumor bulk, spreading of tumor, extranodal sites, LDH andβ2-microglobulin levels; (c) those related to the host-tumor relationship: performance status, presence of B symptoms, serum albumin level, and interleukin secretion; and (d) those related to the physicians: type of treatment, dose intensity of this treatment. Most of these parameters are related to each others and only a few of them keep statistically significant correlation with outcome in multi-parametric studies. New prospective studies with new therapeutic strategies should stratify patients before treatment on these most important prognostic factors.
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