Aqueous humour analysis in Fuchs' heterochromic cyclitis
作者:
MurrayP. I.,
HoekzemaR.,
van HarenM. A.C.,
LuyendijkL.,
KijlstraA.,
期刊:
Current Eye Research
(Taylor Available online 1990)
卷期:
Volume 9,
issue sup1
页码: 53-57
ISSN:0271-3683
年代: 1990
DOI:10.3109/02713689008999420
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Aqueous humour from 23 patients with Fuchs' heterochromic cyclitis (FHC) was analysed by a number of immunological methods. Intraocular IgG synthesis was found in 65% of patients and oligoclonal IgG bands, mainly of the IgG1 subclass, identified in 57%. There was a relative increase in IgG1 (P<0.01) as compared to patients with senile cataract. Local production of the cytokine Interleukin-6 was demonstrated in 63% of patients (P<0.01). Analysis of aqueous by HPLC and SDS-PAGE failed to reveal any abnormalities specific for FHC.These findings add further evidence to the theory of immune dysregulation in this condition.
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