Effects of the respiratory cycle on cardiac output measurementsReproducibility of data enhanced by timing the thermodilution injections in dogs
作者:
JOSEPH ARMENGOL,
GODFREY MAN,
ARAS BALSYS,
ALLAN WELLS,
期刊:
Critical Care Medicine
(OVID Available online 1981)
卷期:
Volume 9,
issue 12
页码: 852-854
ISSN:0090-3493
年代: 1981
出版商: OVID
数据来源: OVID
摘要:
Cardiac output (Q) was measured with the thermodilution technique at 4 points during the respiratory cycle in dogs. Boluses of an ice-cold solution were injected at mid- and end-inspiration while the animals were on intermittent positive-pressure ventilation (IPPV) or after induction of positive end-expiratory pressure (PEEP), with and without induction of experimental respiratory failure. Values were most constant at end-inspiration. During IPPV without respiratory failure, the standard error of 74 measurements at end-inspiration was 5.1% and of 74 measurements randomly selected was 9.8%. Continuous infusion resulted in similar fluctuations in Q (r = 0.92). Values obtained during experimental respiratory failure were not significantly different.The authors conclude that timing the bolus injections with the respiratory cycle enhances the reproducibility of Q values obtained with the thermodilution technique.
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