Summary.A series of experiiiients on rabbits has shown that1) Ether anaesthesia does not alter the citric‐acid content of the blood serum (Ci/s) in a nephrectomized animal. just as little as it does in a normal animal;2) Ci‐elimination in a nephrectomized animal proceeds with the same intensity both before and after an ether anaesthesia;3) After nephrectomy without anaesthesia the Ci/s rises, as it also does after nephrectomy under anaesthesia;4) After nephrectomy without anaesthesia the elimination of administered Ci is considerably slowed up as compared with the elimination before the nephrectcmy.The experiments show that the anaesthesia administered in the Writer's earlier animal experiments did not influence the results of the investigation, which have accordingly been confir