Treatment controversies in medulloblastoma
作者:
Murali Chintagumpala,
Stacey Berg,
Susan Blaney,
期刊:
Current Opinion in Oncology
(OVID Available online 2001)
卷期:
Volume 13,
issue 3
页码: 154-159
ISSN:1040-8746
年代: 2001
出版商: OVID
数据来源: OVID
摘要:
Medulloblastoma, the most common primary malignant brain tumor in children, is a radiosensitive and chemosensitive tumor. Nevertheless, medulloblastoma remains a management challenge for the clinical oncologist, because the optimal sequence and dosage for each treatment modality has not yet been defined. In addition, effective management strategies for medulloblastoma may result in profound neuroendocrine and neuropsychologic sequelae. In this article, we review the clinical and biologic prognostic factors for classifying medulloblastoma, current strategies for the management of this disease, and potential strategies to prevent or minimize long-term treatment sequelae.
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