STONEFISH VENOM: SOME BIOCHEMICAL AND CHEMICAL OBSERVATIONS†
作者:
L Austin,
RG Gillis,
G Youatt,
期刊:
Australian Journal of Experimental Biology and Medical Science
(WILEY Available online 1965)
卷期:
Volume 43,
issue 1
页码: 79-90
ISSN:0004-945X
年代: 1965
DOI:10.1038/icb.1965.6
出版商: Nature Publishing Group
数据来源: WILEY
摘要:
SummaryStonefish venom has been fractionated on carboxymethyl cellulose and Sephadex columns; of the fractions obtained only one was toxic to rats. The active fraction contained a relatively high proportion of aromatic amino acids. Whole venom was examined for enzyme activity and enzyme inhibition; the only significant activity found was that of hyaluronidase. The venom also caused a marked increase in capillary permeability. Ultracentrifuge measurements suggest that the toxic material has a molecular weight of the order of 150,000.
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