Genetical Studies on the Multiple Forms of Human Guanylate Kinase in Man-Chinese Hamster Somatic Cell Hybrids
作者:
Meera Khan,
W.R.T. Los,
P.L. Pearson,
A. Westerveld,
D. Bootsma,
期刊:
Human Heredity
(Karger Available online 1974)
卷期:
Volume 24,
issue 5-6
页码: 415-423
ISSN:0001-5652
年代: 1974
DOI:10.1159/000152700
出版商: S. Karger AG
关键词: Guanylate kinase;Somatic cell hybrids;A-1 linkage group
数据来源: Karger
摘要:
Two of the multiple forms of human guanylate kinase (the components e and c) described by MONN and CHRISTIANSEN could be separated from the guanylate kinase of Chinese hamster in man-Chinese hamster hybrids on cellulose acetate gel. By employing a number of enzyme markers, whose loci have been already assigned to particular human chromosomes, as main markers in man-Chinese hamster hybrids, evidence was gathered to indicate that the components e and c of GuK are determined by two separate loci situated on the human chromosome number 1 distal to the break point q 2.2.
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