Angiotensin Antagonists in Relation to Hypertension
作者:
BumpusF. Merlin,
期刊:
Hospital Practice
(Taylor Available online 1974)
卷期:
Volume 9,
issue 5
页码: 80-92
ISSN:2154-8331
年代: 1974
DOI:10.1080/21548331.1974.11708005
出版商: Taylor&Francis
数据来源: Taylor
摘要:
By substituting (or deleting) amino acids at various positions in the original octapeptide, investigators have developed several analogues of angiotensin II that effectively inhibit the parent molecule's pressure-raising capacity. In addition to clarifying the molecular basis for the biologic actions of angiotensin II, these studies have also opened new approaches to the diagnosis and treatment of certain hypertensive states.
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